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At 14:05 BST the index was down 0.23 per cent to 4,472.11 points, Reuters reports, with banking and retail shares contributing to the drop.
Shares in Lloyds Banking Group - the price of which has been adjusted following the passing of a deadline for taking part in a £4 billon fundraising scheme - were down by over 26 per cent.
Barclays and HSBC fell in value, while firms such as Sainsbury's, Marks & Spencer and Home Retail Group - which owns Argos - also declined.
Lonmin recorded the largest gain, climbing 9.39 per cent, while British Airways and mining companies Rio Tinto and Vedanta Resources also rose.
"Trading seems to be influenced by expected economic data due over the remainder of the week," market strategist Joshua Raymond stated, adding that many investors have been "a little hesitant" during today's trading.
One such piece of information, the UK retail sales statistics, is due for release tomorrow.
