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At 11:17 BST the index was down 0.73 per cent to 4,128.32 points, Reuters reports.
Weaker energy and mining stocks led the decline, which means the market is likely to record four consecutive weeks of falls and may end at its lowest level since late April.
There was a slide of over three per cent for Rio Tinto, which dropped to 1,906.5p per share, while Wolseley shed 2.81 per cent, taking its shares to 1,036p.
Lonmin Amec, Balfour Beatty and Tullow Oil were among the other companies whose shares weakened during morning trading.
"Oil and gas producers were once again the biggest losers on the FTSE, taking over nine points of the index," market analyst Nick Serff noted.
He explained that a negative earnings update from Chevron on Wall Street had a knock-on effect on stock markets around the world.
