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Firms in the financial sector were the worst performers, Reuters reports, with HSBC dropping 3.3 per cent and Barclays, Royal Bank of Scotland, Standard Chartered and Lloyds Banking Group all falling.
As a result, the benchmark index was down 38.31 points to 4,647.47 at 11:53 BST.
Mining companies - including Vedanta Resources, Antofagasta, Anglo American and BHP Billiton - retreated due to the falling price of copper, however Eurasian Natural Resources rose after posting a smaller-than-expected decline in earnings for the first half.
BP, Royal Dutch Shell, Cairn Energy and Tullow Oil all fell in the oil sector, while there were climbs for a number of retailers, including Marks & Spencer, Next and Home Retail Group.
The fall comes after the market rose during the morning session, boosted by gains in oil and mining stocks.
