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The largest index on the British stock exchange shed 1.06 points to move to 5,881.12, Bloomberg reports.
There was a positive move for AstraZeneca as the drugmaker rose by 0.1 per cent to 3,153 pence, despite missing out on US approval for Brilinta, which thins the blood and is a rival to Plavix, the world's second-best selling drug.
What's more, there were gains for Travis Perkins as the building merchant advanced by 1.4 per cent to stand at 1,010 pence.
But there was negative news for pub operator Punch Taverns, which shed one per cent to move down to 66.65 pence.
This comes after the FTSE 100 neared a two-and-a-half-year high yesterday as it moved between gains and losses throughout the day, after the index experienced falls of 0.2 per cent on Wednesday.
Posted by Greg Secker
